“WE WORK FOR YOU AND YOUR HEALTH!”

The motto is brief and exactly showing the company's main objectives: high quality, effectiveness and safety of all produced pharmaceuticals.
Our aim is to provide people with efficient, safe and affordable medical preparations of good quality, to develop and produce products competitive on the local and foreign markets.
Open Joint Stock Company "Farmak" is one of the oldest pharmaceutical companies in Ukraine manufacturing finished medicines and pharmaceutical substances. The company has been established in 1991 on the basis of Kiev Chemical-Pharmaceutical Plant named after M.V.Lomonosov, which started its history with production of synthetic medicines in 1925. Over 80 years of its existence the company has become one of the leading manufacturers of local pharmaceutical industry.
Farmak is a leader among the Ukrainian pharmaceutical manufacturers and is characterized by rapid growth dynamics. In 2007 the rates of sales growth were at 39%.
The enterprise performs refurbishment and technical re-equipment of its facilities according to Good Manufacturing Practice and implements the manufacture of products which are competitive at well-regulated markets.
One of Farmak's main features is the availability of long-term strategic plan of development till 2015. Within the framework of this strategy credit agreement was concluded between Farmak and the European Bank for Reconstruction and Development aimed at financing new production of liquid dosage forms in vials and syringes and production of medications under aseptic conditions.

FARMAK NOWADAYS:

• is leading national pharmaceutical company among the Ukrainian pharmaceutical manufacturers
• is dynamic and fast growing company
• provides about 12% of total production volume of domestic medical products
• more than 18% of manufactured products are exported to CIS countries, Baltic States, Western & Eastern Europe and USA.
• produces over 110 names of medicines
• increases its list of medicines by 15 new products every year
• permanently modernizes production facilities and successfully introduces the GMP standards into its daily manufacturing practice
• has implemented integrated Quality Management System certified by ISO 9001:2000, ISO 14001 and ISO 13485

We export our products to different countries, such as: CIS-countries, Latvia, Lithuania, Estonia, Bulgaria, Poland, Vietnam, USA and others. At present time, some of our products are in the process of registration in Czech Republic, Philippines and New Zealand.

Manufacturing facilities

In the middle of 90s new production lines were started according to the following timetable:

17 000 sq. meters of new production facilities and 6 000 sq. m of office premises and rooms have been added to Farmak over the past decade. Consequently Farmak has sufficient material, technological and manpower resources in order to satisfy demand of domestic and foreign consumers.
We have GMP Certificate on the following production lines:

• production line for manufacturing of tablets (line for production of L-Thyroxine, line for production of Validol);
• production line for manufacturing of ear/eye/nasal drops, sprays (Marchesini line);
• production line for manufacturing of sterile eye and sterile nasal drops (Bottle-pack line);
• production line for manufacturing of vials and cartridges for genetic engineering human insulin under license from Eli Lilly;
• production line for manufacturing of tablets and capsules (500 mln tabs per year);
• production line for manufacturing of vials 5-10-15-20-30-50-100 ml with sterilization (German inspection).

GMP Certificate for the following lines is expected in 2009:

• production line for injectable preparations (Bosch line);
• production line for 30 ml bottles of peroral drops.

Quality assurance system
In the beginning of the 1980s Farmak introduced the integrated system of the quality management of production, which conformed to the domestic requirements existing by that time.
The development of the quality system in accordance to GMP requirements and the international standards ISO 9001:94 was started in 1998. This system was introduced in 2000 and it was certified by the national system of certification in 2001.
During 2001 the quality system was put into operation and during 2002 this system was audited by company TUV Rheinland EUROQUA (Germany) with the participation of the experts on GMP and pharmaceutics. As a result Farmak was granted the international certificate of conformity to ISO 9001:2000.
Since 2001 several competent foreign organizations carried out a number of external expert audits of the manufacturing sites for the conformity to GMP requirements. The results of these audits demonstrated the sufficiently high level of GMP compliance of the enterprise as well as defined the directions of the improvement of company activity.
Technological Areas and Quality Control

Technological areas complied with GMP:

• line for manufacturing of L-thyroxine tablets
• line for manufacturing of drops in polyethylene bottles
• line for manufacturing of drops and sprays
• line for manufacturing of ampoules
• line for manufacturing of Validol tablets
• line for manufacturing of insulin in vials and cartridges

GMP is a system, a way of thinking, Farmak's code of honour. The quality of medical products is secured at all stages of the «life cycle» - from developing and testing till producing and monitoring, storing and selling.
Quality is tested by the quality control division's analytical, microbiological and biological laboratories as well as by workshop labs. Raw materials, intermediate substances, finished products, production and storage conditions, particularly in terms of technological discipline, are subject to compulsory quality control.
Our R&D Laboratories are renovated and re-equipped, supplied with modern equipment according to GLP requirements. Personnel is hired and trained on a selective basis.

PHARMACOTHERAPEUTIC GROUPS OF MEDICINES MANUFACTURED BY FARMAK INTERNATIONAL:

• Endocrinology
• Respiratory
• Cardiovascular and Rheumatology
• Original products
• Diagnostic agents
• Ophthalmic
• Anesthetic
• Antihistamines
• Musculo-sceletal
• Nervous system
• Dermatological

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SALES STRUCTURE BY DOSAGE FORMS
 

We have registration dossiers, prepared according to the CTD standard for the following medical preparations: Farmadex (Dexamethazone) eye drops, Naphthyzine (Naphazoline Nitrate) nasal drops, L-thyroxine tablets, Validol tablets. We are preparing now CTD dossiers for Farmazolin (Xylomethazoline Hydrochloride) drops, sprays, Rhynazoline (Oxymethazoline) drops and spray, Picolax (sodium picosulfate) drops, Pilocarpine hydrochloride eye drops, Uropres (desmopresin) nasal drops and spray, Vial (tetryzolin) eye drops.
The motto of Farmak International
«WE WORK FOR YOU AND YOUR HEALTH» precisely formulates an overall objective of our activity

• maintenance of stable quality
• efficiency and safety of the finished drugs increase of their competitiveness